Cargando…

High glucose protects cardiomyocytes against ischaemia/reperfusion injury by suppressing myocardiocyte apoptosis via circHIPK3/miR‐29b/AKT3 signalling

High glucose promoted expression of AKT3, a direct target gene of miR‐29b, by regulating circHIPK3 that functioned as ceRNA to sponge and down‐regulate miR‐29b. As a potential target gene of miR‐29b, AKT3 plays a crucial role in the pathogenesis of myocardial ischaemia/reperfusion (I/R) injury, and...

Descripción completa

Detalles Bibliográficos
Autores principales: Cheng, Nan, Jin, Chang, Jin, Ping, Zhu, Dan, Hou, Zuoxu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406489/
https://www.ncbi.nlm.nih.gov/pubmed/33951290
http://dx.doi.org/10.1111/jcmm.16527