Kynurenic Acid and Its Synthetic Derivatives Protect Against Sepsis-Associated Neutrophil Activation and Brain Mitochondrial Dysfunction in Rats

BACKGROUND AND AIMS: The systemic host response in sepsis is frequently accompanied by central nervous system (CNS) dysfunction. Evidence suggests that excessive formation of neutrophil extracellular traps (NETs) can increase the permeability of the blood–brain barrier (BBB) and that the evolving mi...

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Detalles Bibliográficos
Autores principales: Poles, Marietta Z., Nászai, Anna, Gulácsi, Levente, Czakó, Bálint L., Gál, Krisztián G., Glenz, Romy J., Dookhun, Dishana, Rutai, Attila, Tallósy, Szabolcs P., Szabó, Andrea, Lőrinczi, Bálint, Szatmári, István, Fülöp, Ferenc, Vécsei, László, Boros, Mihály, Juhász, László, Kaszaki, József
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406694/
https://www.ncbi.nlm.nih.gov/pubmed/34475875
http://dx.doi.org/10.3389/fimmu.2021.717157

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406694/
https://www.ncbi.nlm.nih.gov/pubmed/34475875
http://dx.doi.org/10.3389/fimmu.2021.717157

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