Cargando…
Increased Endogenous GDNF in Mice Protects Against Age-Related Decline in Neuronal Cholinergic Markers
Gradual decline in cholinergic transmission and cognitive function occurs during normal aging, whereas pathological loss of cholinergic function is a hallmark of different types of dementia, including Alzheimer’s disease (AD), Lewy body dementia (LBD), and Parkinson’s disease dementia (PDD). Glial c...
Autores principales: | Mitra, Sumonto, Turconi, Giorgio, Darreh-Shori, Taher, Mätlik, Kärt, Aquilino, Matilde, Eriksdotter, Maria, Andressoo, Jaan-Olle |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406776/ https://www.ncbi.nlm.nih.gov/pubmed/34475820 http://dx.doi.org/10.3389/fnagi.2021.714186 |
Ejemplares similares
-
Two-fold elevation of endogenous GDNF levels in mice improves motor coordination without causing side-effects
por: Mätlik, Kärt, et al.
Publicado: (2018) -
Opposing Spatially Segregated Function of Endogenous GDNF-RET Signaling in Cocaine Addiction
por: Garton, Daniel R., et al.
Publicado: (2023) -
Chronic 2-Fold Elevation of Endogenous GDNF Levels Is Safe and Enhances Motor and Dopaminergic Function in Aged Mice
por: Turconi, Giorgio, et al.
Publicado: (2020) -
CSF and Plasma Cholinergic Markers in Patients With Cognitive Impairment
por: Karami, Azadeh, et al.
Publicado: (2021) -
From microRNA target validation to therapy: lessons learned from studies on BDNF
por: Varendi, Kärt, et al.
Publicado: (2015)