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Predictability of polygenic risk score for progression to dementia and its interaction with APOE ε4 in mild cognitive impairment

BACKGROUND: The combinatorial effect of multiple genetic factors calculated as a polygenic risk score (PRS) has been studied to predict disease progression to Alzheimer’s disease (AD) from mild cognitive impairment (MCI). Previous studies have investigated the performance of PRS in the prediction of...

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Detalles Bibliográficos
Autores principales:	Pyun, Jung-Min, Park, Young Ho, Lee, Keon-Joo, Kim, SangYun, Saykin, Andrew J., Nho, Kwangsik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406896/ https://www.ncbi.nlm.nih.gov/pubmed/34465370 http://dx.doi.org/10.1186/s40035-021-00259-w

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