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The cholesterol esterification inhibitor avasimibe suppresses tumour proliferation and metastasis via the E2F-1 signalling pathway in prostate cancer

BACKGROUND: New effective drugs for prostate cancer (PCa) treatment are urgently needed. Avasimibe was recently identified as a promising drug for anticancer therapies. The main purpose of this study was to explore the effects and the underlying mechanisms of avasimibe in prostate cancer. METHODS: I...

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Detalles Bibliográficos
Autores principales:	Xiong, Kangping, Wang, Gang, Peng, Tianchen, Zhou, Fenfang, Chen, Siming, Liu, Wei, Ju, Lingao, Xiao, Yu, Qian, Kaiyu, Wang, Xinghuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8407011/ https://www.ncbi.nlm.nih.gov/pubmed/34461908 http://dx.doi.org/10.1186/s12935-021-02175-5

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