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UBE2T promotes autophagy via the p53/AMPK/mTOR signaling pathway in lung adenocarcinoma

BACKGROUND: Ubiquitin-conjugating enzyme E2T (UBE2T) acts as an oncogene in various types of cancer. However, the mechanisms behind its oncogenic role remain unclear in lung cancer. This study aims to explore the function and clinical relevance of UBE2T in lung cancer. METHODS: Lentiviral vectors we...

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Detalles Bibliográficos
Autores principales: Zhu, Jinhong, Ao, Haijiao, Liu, Mingdong, Cao, Kui, Ma, Jianqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8407090/
https://www.ncbi.nlm.nih.gov/pubmed/34461934
http://dx.doi.org/10.1186/s12967-021-03056-1

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