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Species-Specific Endotoxin Stimulus Determines Toll-Like Receptor 4- and Caspase 11-Mediated Pathway Activation Characteristics

The innate immune system is the body’s first line of defense against pathogens and its protection against infectious diseases. On the surface of host myeloid cells, Toll-like receptor 4 (TLR4) senses lipopolysaccharide (LPS), the major outer membrane component of Gram-negative bacteria. Intracellula...

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Detalles Bibliográficos
Autores principales:	Ernst, Orna, Khan, Mohd M., Oyler, Benjamin L., Yoon, Sung Hwan, Sun, Jing, Lin, Fang-Yu, Manes, Nathan P., MacKerell, Alexander D., Fraser, Iain D. C., Ernst, Robert K., Goodlett, David R., Nita-Lazar, Aleksandra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8407122/ https://www.ncbi.nlm.nih.gov/pubmed/34342534 http://dx.doi.org/10.1128/mSystems.00306-21

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