Cargando…
Dual PD-L1 and TGF-b blockade in patients with recurrent respiratory papillomatosis
BACKGROUND: Recurrent respiratory papillomatosis (RRP) is a human papillomavirus (HPV) driven neoplastic disorder of the upper aerodigestive tract that causes significant morbidity and can lead to fatal airway obstruction. Prior clinical study demonstrated clinical benefit with the programmed death-...
Autores principales: | Robbins, Yvette, Friedman, Jay, Clavijo, Paul E, Sievers, Cem, Bai, Ke, Donahue, Renee N, Schlom, Jeffrey, Sinkoe, Andrew, Abdul Sater, Houssein, Gulley, James L, Norberg, Scott, Hinrichs, Christian S, Allen, Clint |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8407210/ https://www.ncbi.nlm.nih.gov/pubmed/34462327 http://dx.doi.org/10.1136/jitc-2021-003113 |
Ejemplares similares
-
Comprehensive multiomic characterization of human papillomavirus-driven recurrent respiratory papillomatosis reveals distinct molecular subtypes
por: Sievers, Cem, et al.
Publicado: (2021) -
Bintrafusp alfa, a bifunctional fusion protein targeting TGF-β and PD-L1, in patients with human papillomavirus-associated malignancies
por: Strauss, Julius, et al.
Publicado: (2020) -
Phase I study of a multitargeted recombinant Ad5 PSA/MUC-1/brachyury-based immunotherapy vaccine in patients with metastatic castration-resistant prostate cancer (mCRPC)
por: Bilusic, Marijo, et al.
Publicado: (2021) -
PD-L1 targeting high-affinity NK (t-haNK) cells induce direct antitumor effects and target suppressive MDSC populations
por: Fabian, Kellsye P, et al.
Publicado: (2020) -
Immune correlates of clinical parameters in patients with HPV-associated malignancies treated with bintrafusp alfa
por: Tsai, Yo-Ting, et al.
Publicado: (2022)