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A Systematic Review of Fibrin Glue as an Ideal Treatment for the Pilonidal Disease

Pilonidal sinus is an acquired condition caused by irritation to the hair follicles at the natal cleft, presenting with an abscess or chronic infection. It is prevalent in young adults affecting their productive lifestyle with morbidities. There are varieties of treatment options; however, there is...

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Autores principales: Win, Myat, Went, Terry R, Ruo, Sheila W, Kannan, Amudhan, Dominic, Jerry Lorren, Sultan, Waleed, Kantamaneni, Ketan, Yanamala, Vijaya lakshmi, Tara, Anjli, Elshaikh, Abeer O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8407475/
https://www.ncbi.nlm.nih.gov/pubmed/34513421
http://dx.doi.org/10.7759/cureus.16831
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author Win, Myat
Went, Terry R
Ruo, Sheila W
Kannan, Amudhan
Dominic, Jerry Lorren
Sultan, Waleed
Kantamaneni, Ketan
Yanamala, Vijaya lakshmi
Tara, Anjli
Elshaikh, Abeer O
author_facet Win, Myat
Went, Terry R
Ruo, Sheila W
Kannan, Amudhan
Dominic, Jerry Lorren
Sultan, Waleed
Kantamaneni, Ketan
Yanamala, Vijaya lakshmi
Tara, Anjli
Elshaikh, Abeer O
author_sort Win, Myat
collection PubMed
description Pilonidal sinus is an acquired condition caused by irritation to the hair follicles at the natal cleft, presenting with an abscess or chronic infection. It is prevalent in young adults affecting their productive lifestyle with morbidities. There are varieties of treatment options; however, there is no consensus yet for the ideal procedure. Less invasive procedures have evolved to replace the traditional surgical techniques, which cannot significantly reduce the risks of recurrence and wound complications despite extensive surgeries. We aimed to assess the effect of fibrin glue as a primary treatment after cleaning the sinus in pilonidal sinus disease. We searched for articles from PubMed®, Ovid MEDLINE®, Ovid EMBASE®, and Cochrane CENTRAL. Six studies that included 336 patients in total were analyzed. Fibrin glue treatment in these studies reported a quicker return to normal activities postoperatively, a low rate of infection, and an acceptable rate of recurrence. Thus, fibrin glue seems beneficial in the management of pilonidal disease. However, further high-quality studies are essential to support and confirm this evidence. Future research should also evaluate its cost and implications in the ambulatory service.
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spelling pubmed-84074752021-09-09 A Systematic Review of Fibrin Glue as an Ideal Treatment for the Pilonidal Disease Win, Myat Went, Terry R Ruo, Sheila W Kannan, Amudhan Dominic, Jerry Lorren Sultan, Waleed Kantamaneni, Ketan Yanamala, Vijaya lakshmi Tara, Anjli Elshaikh, Abeer O Cureus General Surgery Pilonidal sinus is an acquired condition caused by irritation to the hair follicles at the natal cleft, presenting with an abscess or chronic infection. It is prevalent in young adults affecting their productive lifestyle with morbidities. There are varieties of treatment options; however, there is no consensus yet for the ideal procedure. Less invasive procedures have evolved to replace the traditional surgical techniques, which cannot significantly reduce the risks of recurrence and wound complications despite extensive surgeries. We aimed to assess the effect of fibrin glue as a primary treatment after cleaning the sinus in pilonidal sinus disease. We searched for articles from PubMed®, Ovid MEDLINE®, Ovid EMBASE®, and Cochrane CENTRAL. Six studies that included 336 patients in total were analyzed. Fibrin glue treatment in these studies reported a quicker return to normal activities postoperatively, a low rate of infection, and an acceptable rate of recurrence. Thus, fibrin glue seems beneficial in the management of pilonidal disease. However, further high-quality studies are essential to support and confirm this evidence. Future research should also evaluate its cost and implications in the ambulatory service. Cureus 2021-08-02 /pmc/articles/PMC8407475/ /pubmed/34513421 http://dx.doi.org/10.7759/cureus.16831 Text en Copyright © 2021, Win et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle General Surgery
Win, Myat
Went, Terry R
Ruo, Sheila W
Kannan, Amudhan
Dominic, Jerry Lorren
Sultan, Waleed
Kantamaneni, Ketan
Yanamala, Vijaya lakshmi
Tara, Anjli
Elshaikh, Abeer O
A Systematic Review of Fibrin Glue as an Ideal Treatment for the Pilonidal Disease
title A Systematic Review of Fibrin Glue as an Ideal Treatment for the Pilonidal Disease
title_full A Systematic Review of Fibrin Glue as an Ideal Treatment for the Pilonidal Disease
title_fullStr A Systematic Review of Fibrin Glue as an Ideal Treatment for the Pilonidal Disease
title_full_unstemmed A Systematic Review of Fibrin Glue as an Ideal Treatment for the Pilonidal Disease
title_short A Systematic Review of Fibrin Glue as an Ideal Treatment for the Pilonidal Disease
title_sort systematic review of fibrin glue as an ideal treatment for the pilonidal disease
topic General Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8407475/
https://www.ncbi.nlm.nih.gov/pubmed/34513421
http://dx.doi.org/10.7759/cureus.16831
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