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TNF-dependent hyperactivation of RIPK1-dependent cytotoxic signaling during embryogenesis and inflammation
In this issue of PLOS Biology, Zhang and colleagues unveil a complex midgestational death during embryogenesis of mice harboring caspase-8 cleavage-resistant receptor-interacting protein (RIP) kinase (RIPK)1. Tumor necrosis factor (TNF) receptor (TNFR)1-dependent signaling drives cell death through...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8407551/ https://www.ncbi.nlm.nih.gov/pubmed/34464377 http://dx.doi.org/10.1371/journal.pbio.3001371 |