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Transcriptome Signature of Immune Cells Post Reovirus Treatment in KRAS Mutated Colorectal Cancer

PURPOSE: Reovirus propagates with high efficiency in KRAS mutated colorectal cancer (CRC). About 45–50% of CRC patients possess a KRAS mutation. Oncolytic reovirus treatment in combination with chemotherapy was tested in patients possessing KRAS mutated metastatic CRC. This study evaluates the biolo...

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Detalles Bibliográficos
Autores principales:	Fogel, Elisha J, Samouha, Avishai, Goel, Sanjay, Maitra, Radhashree
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8407676/ https://www.ncbi.nlm.nih.gov/pubmed/34475783 http://dx.doi.org/10.2147/CMAR.S324203

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