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Outcomes of Infants Undergoing Modified Blalock-Taussig Shunt Procedures in Oman: A retrospective study

OBJECTIVES: A modified Blalock-Taussig (mBT) shunt procedure is a common palliative surgery used to treat infants and children with cyanotic congenital heart disease (CCHD). This study aimed to report the outcomes of infants and children undergoing mBT shunt procedures in Oman. In addition, risk fac...

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Autores principales: Shaikh, Samiuddin, Al-Mukhaini, Khaloud S., Al-Rawahi, Abdul Hakeem, Al-Dafie, Omer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sultan Qaboos University Medical Journal, College of Medicine & Health Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8407913/
https://www.ncbi.nlm.nih.gov/pubmed/34522413
http://dx.doi.org/10.18295/squmj.8.2021.125
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author Shaikh, Samiuddin
Al-Mukhaini, Khaloud S.
Al-Rawahi, Abdul Hakeem
Al-Dafie, Omer
author_facet Shaikh, Samiuddin
Al-Mukhaini, Khaloud S.
Al-Rawahi, Abdul Hakeem
Al-Dafie, Omer
author_sort Shaikh, Samiuddin
collection PubMed
description OBJECTIVES: A modified Blalock-Taussig (mBT) shunt procedure is a common palliative surgery used to treat infants and children with cyanotic congenital heart disease (CCHD). This study aimed to report the outcomes of infants and children undergoing mBT shunt procedures in Oman. In addition, risk factors associated with early mortality, inter-stage mortality and reintervention were assessed. METHODS: This retrospective cohort study was conducted from January 2016 to December 2018 at the National Heart Centre, Muscat, Oman. All paediatric patients with CCHD undergoing mBT shunt procedures as a primary palliative procedure during this period were included. Data were retrieved from electronic hospital records. Kaplan-Meier survival curves were used to describe overall survival. RESULTS: A total of 50 infants and children were included in this study. The in-hospital mortality and interstage mortality rates were 10% and 6.7%, respectively. Preoperative mechanical ventilation (odds ratio [OR] = 3.00, 95% confidence interval [CI]: 1.98–4.76; P = 0.007) and cardiopulmonary bypass (OR = 4.09, 95% CI: 2.44–6.85; P = 0.002) were significant risk factors for early mortality. In-hospital and interval surgical reintervention rates were 12% and 13.3%, respectively. Following the primary shunt procedure, the median time to second-stage surgery was 15.5 months (range: 5.0–34.0 months). CONCLUSION: The findings of this study support those reported in international research regarding the risks associated with mBT shunt surgeries. In particular, preoperative mechanical ventilation and cardiopulmonary bypass were significant risk factors for early mortality.
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spelling pubmed-84079132021-09-13 Outcomes of Infants Undergoing Modified Blalock-Taussig Shunt Procedures in Oman: A retrospective study Shaikh, Samiuddin Al-Mukhaini, Khaloud S. Al-Rawahi, Abdul Hakeem Al-Dafie, Omer Sultan Qaboos Univ Med J Clinical & Basic Research OBJECTIVES: A modified Blalock-Taussig (mBT) shunt procedure is a common palliative surgery used to treat infants and children with cyanotic congenital heart disease (CCHD). This study aimed to report the outcomes of infants and children undergoing mBT shunt procedures in Oman. In addition, risk factors associated with early mortality, inter-stage mortality and reintervention were assessed. METHODS: This retrospective cohort study was conducted from January 2016 to December 2018 at the National Heart Centre, Muscat, Oman. All paediatric patients with CCHD undergoing mBT shunt procedures as a primary palliative procedure during this period were included. Data were retrieved from electronic hospital records. Kaplan-Meier survival curves were used to describe overall survival. RESULTS: A total of 50 infants and children were included in this study. The in-hospital mortality and interstage mortality rates were 10% and 6.7%, respectively. Preoperative mechanical ventilation (odds ratio [OR] = 3.00, 95% confidence interval [CI]: 1.98–4.76; P = 0.007) and cardiopulmonary bypass (OR = 4.09, 95% CI: 2.44–6.85; P = 0.002) were significant risk factors for early mortality. In-hospital and interval surgical reintervention rates were 12% and 13.3%, respectively. Following the primary shunt procedure, the median time to second-stage surgery was 15.5 months (range: 5.0–34.0 months). CONCLUSION: The findings of this study support those reported in international research regarding the risks associated with mBT shunt surgeries. In particular, preoperative mechanical ventilation and cardiopulmonary bypass were significant risk factors for early mortality. Sultan Qaboos University Medical Journal, College of Medicine & Health Sciences 2021-08 2021-08-29 /pmc/articles/PMC8407913/ /pubmed/34522413 http://dx.doi.org/10.18295/squmj.8.2021.125 Text en © Copyright 2021, Sultan Qaboos University Medical Journal, All Rights Reserved https://creativecommons.org/licenses/by-nd/4.0/This work is licensed under a Creative Commons Attribution-NoDerivatives 4.0 International License (https://creativecommons.org/licenses/by-nd/4.0/) .
spellingShingle Clinical & Basic Research
Shaikh, Samiuddin
Al-Mukhaini, Khaloud S.
Al-Rawahi, Abdul Hakeem
Al-Dafie, Omer
Outcomes of Infants Undergoing Modified Blalock-Taussig Shunt Procedures in Oman: A retrospective study
title Outcomes of Infants Undergoing Modified Blalock-Taussig Shunt Procedures in Oman: A retrospective study
title_full Outcomes of Infants Undergoing Modified Blalock-Taussig Shunt Procedures in Oman: A retrospective study
title_fullStr Outcomes of Infants Undergoing Modified Blalock-Taussig Shunt Procedures in Oman: A retrospective study
title_full_unstemmed Outcomes of Infants Undergoing Modified Blalock-Taussig Shunt Procedures in Oman: A retrospective study
title_short Outcomes of Infants Undergoing Modified Blalock-Taussig Shunt Procedures in Oman: A retrospective study
title_sort outcomes of infants undergoing modified blalock-taussig shunt procedures in oman: a retrospective study
topic Clinical & Basic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8407913/
https://www.ncbi.nlm.nih.gov/pubmed/34522413
http://dx.doi.org/10.18295/squmj.8.2021.125
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