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Assessment of seroprevalence of Toxoplasma gondii in blood donors applied to the blood center of Gazi university hospital

BACKGROUND AND OBJECTIVES: Toxoplasmosis is a life-threatening zoonotic infection in immunosuppressive individuals. Determining the prevalence and seropositivity rates of toxoplasmosis in asymptomatic blood donors is crucial in terms of the risk status of the transmission of this infection to the bl...

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Autores principales: Yılmaz, Ayşegül, Yazıcı, Engin, Turk, Can
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8408027/
https://www.ncbi.nlm.nih.gov/pubmed/34540160
http://dx.doi.org/10.18502/ijm.v13i2.5986
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author Yılmaz, Ayşegül
Yazıcı, Engin
Turk, Can
author_facet Yılmaz, Ayşegül
Yazıcı, Engin
Turk, Can
author_sort Yılmaz, Ayşegül
collection PubMed
description BACKGROUND AND OBJECTIVES: Toxoplasmosis is a life-threatening zoonotic infection in immunosuppressive individuals. Determining the prevalence and seropositivity rates of toxoplasmosis in asymptomatic blood donors is crucial in terms of the risk status of the transmission of this infection to the blood recipients. MATERIALS AND METHODS: In this study, the presence and level of the specific Toxoplasma IgG and IgM antibodies in blood donors was investigated by electrochemiluminescence immunoassay (ECLIA). The statistical significance levels between Toxoplasma seropositivity and demographic characteristics of the donors such as age, educational status, raw meat consumption, drinking water supply were examined. RESULTS: Toxoplasma IgG seropositivity was found among the 225 (25.6%) of the donors present in the study group, while IgM seropositivity was detected in 20 donors (2.3%). The number of donors with only IgM (+) was 8 (0.9%). Both IgG and IgM seropositivities were found in 12 donors (1.4%). CONCLUSION: Our study provides information about Toxoplasma seropositivity based on the samples collected from the donors who were admitted to the blood center of a university hospital in Ankara, Turkey. This study demonstrates that Toxoplasma seropositivity is high in the rural areas and the regions where the education level is low.
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spelling pubmed-84080272021-09-16 Assessment of seroprevalence of Toxoplasma gondii in blood donors applied to the blood center of Gazi university hospital Yılmaz, Ayşegül Yazıcı, Engin Turk, Can Iran J Microbiol Original Article BACKGROUND AND OBJECTIVES: Toxoplasmosis is a life-threatening zoonotic infection in immunosuppressive individuals. Determining the prevalence and seropositivity rates of toxoplasmosis in asymptomatic blood donors is crucial in terms of the risk status of the transmission of this infection to the blood recipients. MATERIALS AND METHODS: In this study, the presence and level of the specific Toxoplasma IgG and IgM antibodies in blood donors was investigated by electrochemiluminescence immunoassay (ECLIA). The statistical significance levels between Toxoplasma seropositivity and demographic characteristics of the donors such as age, educational status, raw meat consumption, drinking water supply were examined. RESULTS: Toxoplasma IgG seropositivity was found among the 225 (25.6%) of the donors present in the study group, while IgM seropositivity was detected in 20 donors (2.3%). The number of donors with only IgM (+) was 8 (0.9%). Both IgG and IgM seropositivities were found in 12 donors (1.4%). CONCLUSION: Our study provides information about Toxoplasma seropositivity based on the samples collected from the donors who were admitted to the blood center of a university hospital in Ankara, Turkey. This study demonstrates that Toxoplasma seropositivity is high in the rural areas and the regions where the education level is low. Tehran University of Medical Sciences 2021-04 /pmc/articles/PMC8408027/ /pubmed/34540160 http://dx.doi.org/10.18502/ijm.v13i2.5986 Text en Copyright © 2021 The Authors. Published by Tehran University of Medical Sciences https://creativecommons.org/licenses/by-nc/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International license (https://creativecommons.org/licenses/by-nc/4.0/). Non-commercial uses of the work are permitted, provided the original work is properly cited.
spellingShingle Original Article
Yılmaz, Ayşegül
Yazıcı, Engin
Turk, Can
Assessment of seroprevalence of Toxoplasma gondii in blood donors applied to the blood center of Gazi university hospital
title Assessment of seroprevalence of Toxoplasma gondii in blood donors applied to the blood center of Gazi university hospital
title_full Assessment of seroprevalence of Toxoplasma gondii in blood donors applied to the blood center of Gazi university hospital
title_fullStr Assessment of seroprevalence of Toxoplasma gondii in blood donors applied to the blood center of Gazi university hospital
title_full_unstemmed Assessment of seroprevalence of Toxoplasma gondii in blood donors applied to the blood center of Gazi university hospital
title_short Assessment of seroprevalence of Toxoplasma gondii in blood donors applied to the blood center of Gazi university hospital
title_sort assessment of seroprevalence of toxoplasma gondii in blood donors applied to the blood center of gazi university hospital
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8408027/
https://www.ncbi.nlm.nih.gov/pubmed/34540160
http://dx.doi.org/10.18502/ijm.v13i2.5986
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