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Research progress, challenges and perspectives on PNPLA3 and its variants in Liver Diseases

The human patatin-like phospholipase domain-containing 3 gene (PNPLA3) is highly expressed in liver and adipose tissue and encodes a transmembrane polypeptide chain containing 481 amino acids. The I148M variant of PNPLA3 is a single nucleotide polymorphism, which is related to a variety of liver and...

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Detalles Bibliográficos
Autores principales: Xiang, Hongjiao, Wu, Zecheng, Wang, Junmin, Wu, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8408107/
https://www.ncbi.nlm.nih.gov/pubmed/34476007
http://dx.doi.org/10.7150/jca.57951

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