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Kallistatin limits abdominal aortic aneurysm by attenuating generation of reactive oxygen species and apoptosis

Inflammation, vascular smooth muscle cell apoptosis and oxidative stress are believed to play important roles in abdominal aortic aneurysm (AAA) pathogenesis. Human kallistatin (KAL; gene SERPINA4) is a serine proteinase inhibitor previously shown to inhibit inflammation, apoptosis and oxidative str...

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Detalles Bibliográficos
Autores principales: Krishna, Smriti Murali, Li, Jiaze, Wang, Yutang, Moran, Corey S., Trollope, Alexandra, Huynh, Pacific, Jose, Roby, Biros, Erik, Ma, Jianxing, Golledge, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8408144/
https://www.ncbi.nlm.nih.gov/pubmed/34465809
http://dx.doi.org/10.1038/s41598-021-97042-8

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