Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer

Bone metastasis is an incurable complication of breast cancer. In advanced stages, patients with estrogen-positive tumors experience a significantly higher incidence of bone metastasis (>87%) compared to estrogen-negative patients (<56%). To understand the mechanism of this bone-tropism of ER(...

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Detalles Bibliográficos
Autores principales: Wu, Kerui, Feng, Jiamei, Lyu, Feng, Xing, Fei, Sharma, Sambad, Liu, Yin, Wu, Shih-Ying, Zhao, Dan, Tyagi, Abhishek, Deshpande, Ravindra Pramod, Pei, Xinhong, Ruiz, Marco Gabril, Takahashi, Hiroyuki, Tsuzuki, Shunsuke, Kimura, Takahiro, Mo, Yin-yuan, Shiozawa, Yusuke, Singh, Ravi, Watabe, Kounosuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8408156/
https://www.ncbi.nlm.nih.gov/pubmed/34465793
http://dx.doi.org/10.1038/s41467-021-25473-y

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