Snail/PRMT5/NuRD complex contributes to DNA hypermethylation in cervical cancer by TET1 inhibition

The biological function of PRMT5 remains poorly understood in cervical cancer metastasis. Here, we report that PRMT5 physically associates with the transcription factor Snail and the NuRD(MTA1) complex to form a transcriptional-repressive complex that catalyzes the symmetrical histone dimethylation...

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Detalles Bibliográficos
Autores principales: Gao, Jie, Liu, Ruiqiong, Feng, Dandan, Huang, Wei, Huo, Miaomiao, Zhang, Jingyao, Leng, Shuai, Yang, Yang, Yang, Tianshu, Yin, Xin, Teng, Xu, Yu, Hefen, Yuan, Baowen, Wang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8408166/
https://www.ncbi.nlm.nih.gov/pubmed/33953349
http://dx.doi.org/10.1038/s41418-021-00786-z

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