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MECOM permits pancreatic acinar cell dedifferentiation avoiding cell death under stress conditions

Maintenance of the pancreatic acinar cell phenotype suppresses tumor formation. Hence, repetitive acute or chronic pancreatitis, stress conditions in which the acinar cells dedifferentiate, predispose for cancer formation in the pancreas. Dedifferentiated acinar cells acquire a large panel of duct c...

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Detalles Bibliográficos
Autores principales:	Backx, Elyne, Wauters, Elke, Baldan, Jonathan, Van Bulck, Mathias, Michiels, Ellis, Heremans, Yves, De Paep, Diedert Luc, Kurokawa, Mineo, Goyama, Susumu, Bouwens, Luc, Jacquemin, Patrick, Houbracken, Isabelle, Rooman, Ilse
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8408219/ https://www.ncbi.nlm.nih.gov/pubmed/33762742 http://dx.doi.org/10.1038/s41418-021-00771-6

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