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NOTCH1 signaling promotes protein stability of HER3 through the AKT pathway in squamous cell carcinoma of head and neck

Epidermal growth factor receptor (EGFR) remains the sole druggable molecular target other than the PD1/PD-L1 pathway with meaningful clinical benefit in squamous cell carcinoma of head and neck (SCCHN). Human epidermal growth factor receptor 3 (HER3) confers the resistance to EGFR-targeted treatment...

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Detalles Bibliográficos
Autores principales:	Wang, Yi-Ping, Liu, I-Ju, Chen, Kai-Chi, Wu, Han-Chung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8408252/ https://www.ncbi.nlm.nih.gov/pubmed/34465724 http://dx.doi.org/10.1038/s41389-021-00348-5

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