ALKBH5-mediated m(6)A mRNA methylation governs human embryonic stem cell cardiac commitment

N6-methyladenosine (m(6)A), as the most abundant modification of mammalian messenger RNAs, is essential for tissue development and pathogenesis. However, the biological significance of m(6)A methylation in cardiac differentiation and development remains largely unknown. Here, we identify that the do...

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Detalles Bibliográficos
Autores principales: Han, Zhenbo, Xu, Zihang, Yu, Ying, Cao, Yang, Bao, Zhengyi, Gao, Xinlu, Ye, Danyu, Yan, Gege, Gong, Rui, Xu, Juan, Zhang, Lai, Ma, Wenya, Wang, Xiuxiu, Yang, Fan, Lei, Hong, Tian, Ye, Hu, Shijun, Bamba, Djibril, Li, Ying, Li, Desheng, Li, Changzhu, Wang, Ning, Zhang, Ying, Pan, Zhenwei, Yang, Baofeng, Cai, Benzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8408434/
https://www.ncbi.nlm.nih.gov/pubmed/34513291
http://dx.doi.org/10.1016/j.omtn.2021.05.019

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