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Memory IgM protects endogenous insulin from autoimmune destruction

The enormous diversity of antibody specificities is generated by random rearrangement of immunoglobulin gene segments and is important for general protection against pathogens. Since random rearrangement harbors the risk of producing self‐destructive antibodies, it is assumed that autoreactive antib...

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Detalles Bibliográficos
Autores principales: Amendt, Timm, Jumaa, Hassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8408592/
https://www.ncbi.nlm.nih.gov/pubmed/34369608
http://dx.doi.org/10.15252/embj.2020107621