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Ceruloplasmin deletion in myelinating glial cells induces myelin disruption and oxidative stress in the central and peripheral nervous systems

Ceruloplasmin (Cp) is a ferroxidase enzyme that is essential for cell iron efflux and has been postulated to have a neuroprotective role. During the myelination process, oligodendrocytes (OLs) and Schwann cells (SCs) express high levels of Cp, but the role of this enzyme in glial cell development an...

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Detalles Bibliográficos
Autores principales: Santiago González, D.A., Cheli, V.T., Rosenblum, S.L., Denaroso, G., Paez, P.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8408659/
https://www.ncbi.nlm.nih.gov/pubmed/34474395
http://dx.doi.org/10.1016/j.redox.2021.102118