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Ceruloplasmin deletion in myelinating glial cells induces myelin disruption and oxidative stress in the central and peripheral nervous systems
Ceruloplasmin (Cp) is a ferroxidase enzyme that is essential for cell iron efflux and has been postulated to have a neuroprotective role. During the myelination process, oligodendrocytes (OLs) and Schwann cells (SCs) express high levels of Cp, but the role of this enzyme in glial cell development an...
Autores principales: | Santiago González, D.A., Cheli, V.T., Rosenblum, S.L., Denaroso, G., Paez, P.M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8408659/ https://www.ncbi.nlm.nih.gov/pubmed/34474395 http://dx.doi.org/10.1016/j.redox.2021.102118 |
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