Prognostic significance of genome-wide DNA methylation profiles within the randomized, phase 3, EORTC CATNON trial on non-1p/19q deleted anaplastic glioma

BACKGROUND: Survival in patients with IDH1/2-mutant (mt) anaplastic astrocytomas is highly variable. We have used the prospective phase 3 CATNON trial to identify molecular factors related to outcome in IDH1/2mt anaplastic astrocytoma patients. METHODS: The CATNON trial randomized 751 adult patients...

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Detalles Bibliográficos
Autores principales: Tesileanu, C Mircea S, van den Bent, Martin J, Sanson, Marc, Wick, Wolfgang, Brandes, Alba A, Clement, Paul M, Erridge, Sara C, Vogelbaum, Michael A, Nowak, Anna K, Baurain, Jean F, Mason, Warren P, Wheeler, Helen, Chinot, Olivier L, Gill, Sanjeev, Griffin, Matthew, Rogers, Leland, Taal, Walter, Rudà, Roberta, Weller, Michael, McBain, Catherine, van Linde, Myra E, Sabedot, Thais S, Hoogstrate, Youri, von Deimling, Andreas, de Heer, Iris, van IJcken, Wilfred F J, Brouwer, Rutger W W, Aldape, Kenneth, Jenkins, Robert B, Dubbink, Hendrikus J, Kros, Johan M, Wesseling, Pieter, Cheung, Kin Jip, Golfinopoulos, Vassilis, Baumert, Brigitta G, Gorlia, Thierry, Noushmehr, Houtan, French, Pim J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Clinical Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8408862/
https://www.ncbi.nlm.nih.gov/pubmed/33914057
http://dx.doi.org/10.1093/neuonc/noab088

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