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Hippocampal glucose uptake as a surrogate of metabolic change of microglia in Alzheimer’s disease

ABSTRACT: BACKGROUND: Dynamically altered microglia play an important role in the progression of Alzheimer’s disease (AD). Here, we found a close association of the metabolic reconfiguration of microglia with increased hippocampal glucose uptake on [(18)F]fluorodeoxyglucose (FDG) PET. METHODS: We us...

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Detalles Bibliográficos
Autores principales: Choi, Hongyoon, Choi, Yoori, Lee, Eun Ji, Kim, Hyun, Lee, Youngsun, Kwon, Seokjun, Hwang, Do Won, Lee, Dong Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8408933/
https://www.ncbi.nlm.nih.gov/pubmed/34465358
http://dx.doi.org/10.1186/s12974-021-02244-6