Cargando…

Hippocampal glucose uptake as a surrogate of metabolic change of microglia in Alzheimer’s disease

ABSTRACT: BACKGROUND: Dynamically altered microglia play an important role in the progression of Alzheimer’s disease (AD). Here, we found a close association of the metabolic reconfiguration of microglia with increased hippocampal glucose uptake on [(18)F]fluorodeoxyglucose (FDG) PET. METHODS: We us...

Descripción completa

Detalles Bibliográficos
Autores principales:	Choi, Hongyoon, Choi, Yoori, Lee, Eun Ji, Kim, Hyun, Lee, Youngsun, Kwon, Seokjun, Hwang, Do Won, Lee, Dong Soo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8408933/ https://www.ncbi.nlm.nih.gov/pubmed/34465358 http://dx.doi.org/10.1186/s12974-021-02244-6

Ejemplares similares

Improvement of glymphatic–lymphatic drainage of beta-amyloid by focused ultrasound in Alzheimer’s disease model
por: Lee, Youngsun, et al.
Publicado: (2020)

Maturation of metabolic connectivity of the adolescent rat brain
por: Choi, Hongyoon, et al.
Publicado: (2015)

Human neural stem cell-derived extracellular vesicles protect against Parkinson’s disease pathologies
por: Lee, Eun Ji, et al.
Publicado: (2022)

Fluorescence imaging of in vivo miR-124a-induced neurogenesis of neuronal progenitor cells using neuron-specific reporters
por: Jang, Jaeho, et al.
Publicado: (2016)

Extracellular Vesicles Induce an Aggressive Phenotype in Luminal Breast Cancer Cells Via PKM2 Phosphorylation
por: Kang, Seo Young, et al.
Publicado: (2021)

Different Glucose Metabolic Features According to Cancer and Immune Cells in the Tumor Microenvironment
por: Choi, Hongyoon, et al.
Publicado: (2021)

Transgenic Mouse Expressing Optical MicroRNA Reporter for Monitoring MicroRNA-124 Action during Development
por: Choi, Yoori, et al.
Publicado: (2016)

(18)F‐FDG uptake in denervated muscles of patients with peripheral nerve injury
por: Choi, Ji Soo, et al.
Publicado: (2019)

Microglia in Alzheimer's Disease
por: Jin, Lee-Way
Publicado: (2012)

Illuminating the physiology of extracellular vesicles
por: Choi, Hongyoon, et al.
Publicado: (2016)

Detection of intra-brain cytoplasmic 1 (BC1) long noncoding RNA using graphene oxide-fluorescence beacon detector
por: Kim, Mee Young, et al.
Publicado: (2016)

Differences in Tumor Immune Microenvironment in Metastatic Sites of Breast Cancer
por: Lee, Hyunjong, et al.
Publicado: (2021)

γ-Oryzanol Enhances Adipocyte Differentiation and Glucose Uptake
por: Jung, Chang Hwa, et al.
Publicado: (2015)

Predicting Aging of Brain Metabolic Topography Using Variational Autoencoder
por: Choi, Hongyoon, et al.
Publicado: (2018)

Discovery of molecular features underlying the morphological landscape by integrating spatial transcriptomic data with deep features of tissue images
por: Bae, Sungwoo, et al.
Publicado: (2021)

spSeudoMap: cell type mapping of spatial transcriptomics using unmatched single-cell RNA-seq data
por: Bae, Sungwoo, et al.
Publicado: (2023)

Glucose Hypometabolism in Hippocampal Subdivisions in Alzheimer's Disease: A Pilot Study Using High-Resolution (18)F-FDG PET and 7.0-T MRI
por: Choi, Eun-Jung, et al.
Publicado: (2018)

Systematic evaluation of scoring methods for Ki67 as a surrogate for 21-gene recurrence score
por: Paik, Soonmyung, et al.
Publicado: (2021)

Involvement of Heme Oxygenase-1 Induction in the Cytoprotective and Immunomodulatory Activities of Viola patrinii in Murine Hippocampal and Microglia Cells
por: Li, Bin, et al.
Publicado: (2012)

Investigating the Clinico-Molecular and Immunological Evolution of Lung Adenocarcinoma Using Pseudotime Analysis
por: Lee, Hyunjong, et al.
Publicado: (2022)

Neuritin Attenuates Cognitive Function Impairments in Tg2576 Mouse Model of Alzheimer's Disease
por: Choi, Yoori, et al.
Publicado: (2014)

Disrupted brain metabolic connectivity in a 6-OHDA-induced mouse model of Parkinson’s disease examined using persistent homology-based analysis
por: Im, Hyung-Jun, et al.
Publicado: (2016)

Noninvasive imaging of radiolabeled exosome-mimetic nanovesicle using (99m)Tc-HMPAO
por: Hwang, Do Won, et al.
Publicado: (2015)

Measurement of Precuneal and Hippocampal Volumes Using Magnetic Resonance Volumetry in Alzheimer's Disease
por: Ryu, Seon-Young, et al.
Publicado: (2010)

Reduction of Amyloid Burden by Proliferated Homeostatic Microglia in Toxoplasma gondii-Infected Alzheimer’s Disease Model Mice
por: Shin, Ji-Hun, et al.
Publicado: (2021)

APOE and TREM2 regulate amyloid responsive microglia in Alzheimer’s disease
por: Nguyen, Aivi T., et al.
Publicado: (2020)

Association of androgen receptor expression with glucose metabolic features in triple-negative breast cancer
por: Lee, Reeree, et al.
Publicado: (2022)

Correlation between standardized uptake value of (18)F-FDG PET/CT and conductivity with pathologic prognostic factors in breast cancer
por: Shin, Dong-Joo, et al.
Publicado: (2023)

Silica-Based Nanoparticle Uptake and Cellular Response by Primary Microglia
por: Choi, Judy, et al.
Publicado: (2010)

Enhancement of Glucose Uptake by Meso-Dihydroguaiaretic Acid through GLUT4 Up-Regulation in 3T3-L1 Adipocytes
por: Lee, Anna, et al.
Publicado: (2017)

Reciprocal change in Glucose metabolism of Cancer and Immune Cells mediated by different Glucose Transporters predicts Immunotherapy response
por: Na, Kwon Joong, et al.
Publicado: (2020)

Glucose–Thymidine Ratio as a Metabolism Index Using (18)F-FDG and (18)F-FLT PET Uptake as a Potential Imaging Biomarker for Evaluating Immune Checkpoint Inhibitor Therapy
por: Oh, Sera, et al.
Publicado: (2022)

Aged Microglia in Neurodegenerative Diseases: Microglia Lifespan and Culture Methods
por: Yoo, Hyun-Jung, et al.
Publicado: (2022)

Inhibitory Neural Network’s Impairments at Hippocampal CA1 LTP in an Aged Transgenic Mouse Model of Alzheimer’s Disease
por: Seo, Hyeon Jeong, et al.
Publicado: (2021)

Deep learning only by normal brain PET identify unheralded brain anomalies
por: Choi, Hongyoon, et al.
Publicado: (2019)

FDG uptake, a surrogate of tumour hypoxia?
por: Dierckx, Rudi Andre, et al.
Publicado: (2008)

Microglia – mediated immunity partly contributes to the genetic association between Alzheimer’s disease and hippocampal volume
por: Lancaster, T.M., et al.
Publicado: (2019)

The Stimulatory Effect of Essential Fatty Acids on Glucose Uptake Involves Both Akt and AMPK Activation in C2C12 Skeletal Muscle Cells
por: Park, So Yeon, et al.
Publicado: (2014)

The role of microglia in adult hippocampal neurogenesis
por: Gemma, Carmelina, et al.
Publicado: (2013)

Reaction of the Hippocampal Microglia to Hyperbaric Oxygen
por: Kirik, O. V., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_dc2lkjdd0tgl6bepc9rm3bhdv6