The biology of bone morphogenetic protein signaling pathway in cerebrovascular system

Bone morphogenetic protein belongs to transcription growth factor superfamily β; bone morphogenetic protein signal pathway regulates cell proliferation, differentiation, and apoptosis among different tissues. Cerebrovascular system supplies sufficient oxygen and blood into brain to maintain its norm...

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Autores principales: Tang, Haishuang, Zhang, Xiaoxi, Xue, Gaici, Xu, Fengfeng, Wang, Qingsong, Yang, Pengfei, Hong, Bo, Xu, Yi, Huang, Qinghai, Liu, Jianmin, Zuo, Qiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8408949/
https://www.ncbi.nlm.nih.gov/pubmed/34465399
http://dx.doi.org/10.1186/s41016-021-00254-0
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author Tang, Haishuang
Zhang, Xiaoxi
Xue, Gaici
Xu, Fengfeng
Wang, Qingsong
Yang, Pengfei
Hong, Bo
Xu, Yi
Huang, Qinghai
Liu, Jianmin
Zuo, Qiao
author_facet Tang, Haishuang
Zhang, Xiaoxi
Xue, Gaici
Xu, Fengfeng
Wang, Qingsong
Yang, Pengfei
Hong, Bo
Xu, Yi
Huang, Qinghai
Liu, Jianmin
Zuo, Qiao
author_sort Tang, Haishuang
collection PubMed
description Bone morphogenetic protein belongs to transcription growth factor superfamily β; bone morphogenetic protein signal pathway regulates cell proliferation, differentiation, and apoptosis among different tissues. Cerebrovascular system supplies sufficient oxygen and blood into brain to maintain its normal function. The disorder of cerebrovascular system will result into serious cerebrovascular diseases, which is gradually becoming a major threat to human health in modern society. In recent decades, many studies have revealed the underlying biology and mechanism of bone morphogenetic protein signal pathway played in cerebrovascular system. This review will discuss the relationship between the two aspects, aiming to provide new perspective for non-invasive treatment and basic research of cerebrovascular diseases.
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spelling pubmed-84089492021-09-02 The biology of bone morphogenetic protein signaling pathway in cerebrovascular system Tang, Haishuang Zhang, Xiaoxi Xue, Gaici Xu, Fengfeng Wang, Qingsong Yang, Pengfei Hong, Bo Xu, Yi Huang, Qinghai Liu, Jianmin Zuo, Qiao Chin Neurosurg J Review Bone morphogenetic protein belongs to transcription growth factor superfamily β; bone morphogenetic protein signal pathway regulates cell proliferation, differentiation, and apoptosis among different tissues. Cerebrovascular system supplies sufficient oxygen and blood into brain to maintain its normal function. The disorder of cerebrovascular system will result into serious cerebrovascular diseases, which is gradually becoming a major threat to human health in modern society. In recent decades, many studies have revealed the underlying biology and mechanism of bone morphogenetic protein signal pathway played in cerebrovascular system. This review will discuss the relationship between the two aspects, aiming to provide new perspective for non-invasive treatment and basic research of cerebrovascular diseases. BioMed Central 2021-09-01 /pmc/articles/PMC8408949/ /pubmed/34465399 http://dx.doi.org/10.1186/s41016-021-00254-0 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Tang, Haishuang
Zhang, Xiaoxi
Xue, Gaici
Xu, Fengfeng
Wang, Qingsong
Yang, Pengfei
Hong, Bo
Xu, Yi
Huang, Qinghai
Liu, Jianmin
Zuo, Qiao
The biology of bone morphogenetic protein signaling pathway in cerebrovascular system
title The biology of bone morphogenetic protein signaling pathway in cerebrovascular system
title_full The biology of bone morphogenetic protein signaling pathway in cerebrovascular system
title_fullStr The biology of bone morphogenetic protein signaling pathway in cerebrovascular system
title_full_unstemmed The biology of bone morphogenetic protein signaling pathway in cerebrovascular system
title_short The biology of bone morphogenetic protein signaling pathway in cerebrovascular system
title_sort biology of bone morphogenetic protein signaling pathway in cerebrovascular system
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8408949/
https://www.ncbi.nlm.nih.gov/pubmed/34465399
http://dx.doi.org/10.1186/s41016-021-00254-0
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