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Sevoflurane and isoflurane inhibit KCl-induced, Rho kinase-mediated, and PI3K-participated vasoconstriction in aged diabetic rat aortas

BACKGROUND: The mechanism of volatile anesthetics on vascular smooth muscle (VSM) contraction in the setting of diabetes mellitus (DM) remains unclear. The current study was designed to determine the effects of sevoflurane (SEVO) and isoflurane (ISO) on phosphoinositide 3-kinase (PI3K) and Rho kinas...

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Detalles Bibliográficos
Autores principales:	Yang, Shaozhong, Liu, Yu, Huang, Shanshan, Jin, Feihong, Qi, Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8408970/ https://www.ncbi.nlm.nih.gov/pubmed/34470604 http://dx.doi.org/10.1186/s12871-021-01425-3

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