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Inhibition of HDAC1 alleviates monocrotaline-induced pulmonary arterial remodeling through up-regulation of miR-34a

BACKGROUND: It has been found that up-regulation of histone deacetylases 1 (HDAC1) is involved in the development of pulmonary arterial hypertension (PAH). However, it is still unclear whether inhibition of HDAC1 suppresses the development of PAH via restoring miR-34a level in monocrotaline (MCT)-in...

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Detalles Bibliográficos
Autores principales:	Li, Fangwei, Wang, Dan, Wang, Hong, Chen, Lijun, Sun, Xilu, Wan, Yixin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8408973/ https://www.ncbi.nlm.nih.gov/pubmed/34465322 http://dx.doi.org/10.1186/s12931-021-01832-7

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