Monitoring of clonal evolution of acute myeloid leukemia identifies the leukemia subtype, clinical outcome and potential new drug targets for post-remission strategies or relapse

In cases of treatment failure in acute myeloid leukemia (AML), the utility of mutational profiling in primary refractoriness and relapse is not established. We undertook a perspective study using next-generation sequencing (NGS) of clinical follow-up samples (n=91) from 23 patients with AML with the...

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Detalles Bibliográficos
Autores principales: Onecha, Esther, Rapado, Inmaculada, Luz Morales, María, Carreño-Tarragona, Gonzalo, Martinez-Sanchez, Pilar, Gutierrez, Xabier, Pina, José María Sánchez, Linares, María, Gallardo, Miguel, Martinez-López, Joaquín, Ayala, Rosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409047/
https://www.ncbi.nlm.nih.gov/pubmed/32732356
http://dx.doi.org/10.3324/haematol.2020.254623

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