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TooManyPeaks identifies drug-resistant-specific regulatory elements from single-cell leukemic epigenomes

Emerging single-cell epigenomic assays are used to investigate the heterogeneity of chromatin activity and its function. However, identifying cells with distinct regulatory elements and clearly visualizing their relationships remains challenging. To this end, we introduce TooManyPeaks to address the...

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Detalles Bibliográficos
Autores principales: Schwartz, Gregory W., Zhou, Yeqiao, Petrovic, Jelena, Pear, Warren S., Faryabi, Robert B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409102/
https://www.ncbi.nlm.nih.gov/pubmed/34433064
http://dx.doi.org/10.1016/j.celrep.2021.109575