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Case series of COVID-19 patients from the Qinghai-Tibetan Plateau Area in China
BACKGROUND: Coronavirus disease 2019 (COVID-19) is a serious infection caused by the new coronavirus severe acute respiratory syndrome coronavirus 2. The disease was first identified in December 2019 and has caused significant morbidity and mortality worldwide. AIM: To explore the clinical character...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Baishideng Publishing Group Inc
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409201/ https://www.ncbi.nlm.nih.gov/pubmed/34540958 http://dx.doi.org/10.12998/wjcc.v9.i24.7032 |
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author | Li, Ji-Jie Zhang, Hui-Qiong Li, Pei-Jun Xin, Zhi-Lan Xi, Ai-Qi Ding, Yue-He Yang, Zheng-Ping Ma, Si-Qing |
author_facet | Li, Ji-Jie Zhang, Hui-Qiong Li, Pei-Jun Xin, Zhi-Lan Xi, Ai-Qi Ding, Yue-He Yang, Zheng-Ping Ma, Si-Qing |
author_sort | Li, Ji-Jie |
collection | PubMed |
description | BACKGROUND: Coronavirus disease 2019 (COVID-19) is a serious infection caused by the new coronavirus severe acute respiratory syndrome coronavirus 2. The disease was first identified in December 2019 and has caused significant morbidity and mortality worldwide. AIM: To explore the clinical characteristics and treatments for COVID-19 in the Qinghai-Tibetan Plateau Area in China. METHODS: We retrospectively analyzed the blood cell counts (neutrophils and lymphocytes), blood gas analysis, and thoracic computed tomography changes of patients from Qinghai Province before, during, and after treatment (January 23, 2020 to February 21, 2020). In addition, we summarized and analyzed the information of critical patients. All data were analyzed using SPSS 17.0 (SPSS Inc., Chicago, IL, United States). The quantitative and count variables are represented as the mean ± SD and n (%), respectively. RESULTS: The main symptoms and signs of patients with COVID-19 were fever, dry cough, cough with phlegm, difficulty breathing, and respiratory distress with a respiration rate ≥ 30 times/min, finger oxygen saturation ≤ 93% in the resting state, and oxygenation index less than 200 but greater than 100 (after altitude correction). Eighteen patients with COVID-19, of whom three were critical, and the others were in a mild condition, were included. The main manifestations included fever, dry cough, and fatigue. Three patients developed difficulty breathing and had a fever. They were eventually cured and discharged. Adjuvant examinations showed one case with reduced white cell count (6%) (< 4 × 10(9)/L), six with reduced count of lymphocytes (33%) (< 0.8 × 10(9)/L), and one with abnormal blood glucose level. All 18 patients were discharged, and no death occurred. CONCLUSION: Our findings provide critical insight into assessing the clinical diagnosis and treatment for COVID-19 in the Tibetan plateau area. |
format | Online Article Text |
id | pubmed-8409201 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Baishideng Publishing Group Inc |
record_format | MEDLINE/PubMed |
spelling | pubmed-84092012021-09-16 Case series of COVID-19 patients from the Qinghai-Tibetan Plateau Area in China Li, Ji-Jie Zhang, Hui-Qiong Li, Pei-Jun Xin, Zhi-Lan Xi, Ai-Qi Ding, Yue-He Yang, Zheng-Ping Ma, Si-Qing World J Clin Cases Retrospective Study BACKGROUND: Coronavirus disease 2019 (COVID-19) is a serious infection caused by the new coronavirus severe acute respiratory syndrome coronavirus 2. The disease was first identified in December 2019 and has caused significant morbidity and mortality worldwide. AIM: To explore the clinical characteristics and treatments for COVID-19 in the Qinghai-Tibetan Plateau Area in China. METHODS: We retrospectively analyzed the blood cell counts (neutrophils and lymphocytes), blood gas analysis, and thoracic computed tomography changes of patients from Qinghai Province before, during, and after treatment (January 23, 2020 to February 21, 2020). In addition, we summarized and analyzed the information of critical patients. All data were analyzed using SPSS 17.0 (SPSS Inc., Chicago, IL, United States). The quantitative and count variables are represented as the mean ± SD and n (%), respectively. RESULTS: The main symptoms and signs of patients with COVID-19 were fever, dry cough, cough with phlegm, difficulty breathing, and respiratory distress with a respiration rate ≥ 30 times/min, finger oxygen saturation ≤ 93% in the resting state, and oxygenation index less than 200 but greater than 100 (after altitude correction). Eighteen patients with COVID-19, of whom three were critical, and the others were in a mild condition, were included. The main manifestations included fever, dry cough, and fatigue. Three patients developed difficulty breathing and had a fever. They were eventually cured and discharged. Adjuvant examinations showed one case with reduced white cell count (6%) (< 4 × 10(9)/L), six with reduced count of lymphocytes (33%) (< 0.8 × 10(9)/L), and one with abnormal blood glucose level. All 18 patients were discharged, and no death occurred. CONCLUSION: Our findings provide critical insight into assessing the clinical diagnosis and treatment for COVID-19 in the Tibetan plateau area. Baishideng Publishing Group Inc 2021-08-26 2021-08-26 /pmc/articles/PMC8409201/ /pubmed/34540958 http://dx.doi.org/10.12998/wjcc.v9.i24.7032 Text en ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. |
spellingShingle | Retrospective Study Li, Ji-Jie Zhang, Hui-Qiong Li, Pei-Jun Xin, Zhi-Lan Xi, Ai-Qi Ding, Yue-He Yang, Zheng-Ping Ma, Si-Qing Case series of COVID-19 patients from the Qinghai-Tibetan Plateau Area in China |
title | Case series of COVID-19 patients from the Qinghai-Tibetan Plateau Area in China |
title_full | Case series of COVID-19 patients from the Qinghai-Tibetan Plateau Area in China |
title_fullStr | Case series of COVID-19 patients from the Qinghai-Tibetan Plateau Area in China |
title_full_unstemmed | Case series of COVID-19 patients from the Qinghai-Tibetan Plateau Area in China |
title_short | Case series of COVID-19 patients from the Qinghai-Tibetan Plateau Area in China |
title_sort | case series of covid-19 patients from the qinghai-tibetan plateau area in china |
topic | Retrospective Study |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409201/ https://www.ncbi.nlm.nih.gov/pubmed/34540958 http://dx.doi.org/10.12998/wjcc.v9.i24.7032 |
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