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Exercise-induced oxidative stress and melatonin supplementation: current evidence

Melatonin possesses the indoleamine structure and exerts antioxidant and anti-inflammatory actions and other physiological properties. Physical exercise can influence secretion of melatonin. Melatonin is used as a natural supplement among athletes to regulate sleep cycles and protect muscles against...

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Autores principales: Kruk, Joanna, Aboul-Enein, Basil Hassan, Duchnik, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409271/
https://www.ncbi.nlm.nih.gov/pubmed/34470608
http://dx.doi.org/10.1186/s12576-021-00812-2
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author Kruk, Joanna
Aboul-Enein, Basil Hassan
Duchnik, Ewa
author_facet Kruk, Joanna
Aboul-Enein, Basil Hassan
Duchnik, Ewa
author_sort Kruk, Joanna
collection PubMed
description Melatonin possesses the indoleamine structure and exerts antioxidant and anti-inflammatory actions and other physiological properties. Physical exercise can influence secretion of melatonin. Melatonin is used as a natural supplement among athletes to regulate sleep cycles and protect muscles against oxidative damage. Despite decades of research, there is still a lack of a comprehensive and critical review on melatonin supplementation and physical activity relationship. The aim of this literature review is to examine the antioxidant, anti-inflammatory and other biological functions played by melatonin with reference to the effect of physical exercise on melatonin secretion and the effect of this compound supplementation on exercise-induced oxidative stress in athletes. Evidence shows that intense exercises disturb antioxidant status of competitive athletes, whereas supplementation with melatonin strengthens antioxidant status in trained athletes in various sports as the compound showed high potency in reduction of the oxidative stress and inflammation markers generated during intense and prolonged exercise.
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spelling pubmed-84092712021-09-01 Exercise-induced oxidative stress and melatonin supplementation: current evidence Kruk, Joanna Aboul-Enein, Basil Hassan Duchnik, Ewa J Physiol Sci Review Melatonin possesses the indoleamine structure and exerts antioxidant and anti-inflammatory actions and other physiological properties. Physical exercise can influence secretion of melatonin. Melatonin is used as a natural supplement among athletes to regulate sleep cycles and protect muscles against oxidative damage. Despite decades of research, there is still a lack of a comprehensive and critical review on melatonin supplementation and physical activity relationship. The aim of this literature review is to examine the antioxidant, anti-inflammatory and other biological functions played by melatonin with reference to the effect of physical exercise on melatonin secretion and the effect of this compound supplementation on exercise-induced oxidative stress in athletes. Evidence shows that intense exercises disturb antioxidant status of competitive athletes, whereas supplementation with melatonin strengthens antioxidant status in trained athletes in various sports as the compound showed high potency in reduction of the oxidative stress and inflammation markers generated during intense and prolonged exercise. BioMed Central 2021-09-01 2021 /pmc/articles/PMC8409271/ /pubmed/34470608 http://dx.doi.org/10.1186/s12576-021-00812-2 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Review
Kruk, Joanna
Aboul-Enein, Basil Hassan
Duchnik, Ewa
Exercise-induced oxidative stress and melatonin supplementation: current evidence
title Exercise-induced oxidative stress and melatonin supplementation: current evidence
title_full Exercise-induced oxidative stress and melatonin supplementation: current evidence
title_fullStr Exercise-induced oxidative stress and melatonin supplementation: current evidence
title_full_unstemmed Exercise-induced oxidative stress and melatonin supplementation: current evidence
title_short Exercise-induced oxidative stress and melatonin supplementation: current evidence
title_sort exercise-induced oxidative stress and melatonin supplementation: current evidence
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409271/
https://www.ncbi.nlm.nih.gov/pubmed/34470608
http://dx.doi.org/10.1186/s12576-021-00812-2
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