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NDR/LATS‐family protein kinase genes are indispensable for embryogenesis in Arabidopsis
NDR/LATS‐family protein kinases are conserved among eukaryotes. These protein kinases in yeast and animals phosphorylate specific targets and regulate the cell cycle. Arabidopsis thaliana has eight NDR/LATS‐family protein kinase genes (NDR1‐8), of which NDR2, NDR4, and NDR5 are involved in regulatin...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409290/ https://www.ncbi.nlm.nih.gov/pubmed/34320276 http://dx.doi.org/10.1002/2211-5463.13257 |
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author | Yoon, Hyuk Sung Fujino, Kaien Liu, Shenkui Takano, Tetsuo Tsugama, Daisuke |
author_facet | Yoon, Hyuk Sung Fujino, Kaien Liu, Shenkui Takano, Tetsuo Tsugama, Daisuke |
author_sort | Yoon, Hyuk Sung |
collection | PubMed |
description | NDR/LATS‐family protein kinases are conserved among eukaryotes. These protein kinases in yeast and animals phosphorylate specific targets and regulate the cell cycle. Arabidopsis thaliana has eight NDR/LATS‐family protein kinase genes (NDR1‐8), of which NDR2, NDR4, and NDR5 are involved in regulating pollen development. However, the functions of the other NDR/LATS‐family protein kinase genes in plants are unclear. Here, we show that three putative phosphorylation sites of an Arabidopsis basic leucine zipper transcription factor, VIP1, correspond to NDR/LATS‐family protein kinase phosphorylation motifs and that two of these three sites are phosphorylated by NDR2, NDR3, or NDR8 in vitro. Expression of NDR1‐8 was detected in various tissues. An NDR4 NDR6 NDR7 NDR8 quadruple mutation caused embryonic lethality These results suggest that different NDR/LATS‐family protein kinases in plants have distinct physiological roles. |
format | Online Article Text |
id | pubmed-8409290 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-84092902021-09-03 NDR/LATS‐family protein kinase genes are indispensable for embryogenesis in Arabidopsis Yoon, Hyuk Sung Fujino, Kaien Liu, Shenkui Takano, Tetsuo Tsugama, Daisuke FEBS Open Bio Research Articles NDR/LATS‐family protein kinases are conserved among eukaryotes. These protein kinases in yeast and animals phosphorylate specific targets and regulate the cell cycle. Arabidopsis thaliana has eight NDR/LATS‐family protein kinase genes (NDR1‐8), of which NDR2, NDR4, and NDR5 are involved in regulating pollen development. However, the functions of the other NDR/LATS‐family protein kinase genes in plants are unclear. Here, we show that three putative phosphorylation sites of an Arabidopsis basic leucine zipper transcription factor, VIP1, correspond to NDR/LATS‐family protein kinase phosphorylation motifs and that two of these three sites are phosphorylated by NDR2, NDR3, or NDR8 in vitro. Expression of NDR1‐8 was detected in various tissues. An NDR4 NDR6 NDR7 NDR8 quadruple mutation caused embryonic lethality These results suggest that different NDR/LATS‐family protein kinases in plants have distinct physiological roles. John Wiley and Sons Inc. 2021-08-06 /pmc/articles/PMC8409290/ /pubmed/34320276 http://dx.doi.org/10.1002/2211-5463.13257 Text en © 2021 The Authors. FEBS Open Bio published by John Wiley & Sons Ltd on behalf of Federation of European Biochemical Societies https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Articles Yoon, Hyuk Sung Fujino, Kaien Liu, Shenkui Takano, Tetsuo Tsugama, Daisuke NDR/LATS‐family protein kinase genes are indispensable for embryogenesis in Arabidopsis |
title | NDR/LATS‐family protein kinase genes are indispensable for embryogenesis in Arabidopsis |
title_full | NDR/LATS‐family protein kinase genes are indispensable for embryogenesis in Arabidopsis |
title_fullStr | NDR/LATS‐family protein kinase genes are indispensable for embryogenesis in Arabidopsis |
title_full_unstemmed | NDR/LATS‐family protein kinase genes are indispensable for embryogenesis in Arabidopsis |
title_short | NDR/LATS‐family protein kinase genes are indispensable for embryogenesis in Arabidopsis |
title_sort | ndr/lats‐family protein kinase genes are indispensable for embryogenesis in arabidopsis |
topic | Research Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409290/ https://www.ncbi.nlm.nih.gov/pubmed/34320276 http://dx.doi.org/10.1002/2211-5463.13257 |
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