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Carcinoembryonic antigen as a specific glycoprotein ligand of rBC2LCN lectin on pancreatic ductal adenocarcinoma cells
The rBC2LCN lectin, known as a stem cell marker probe that binds to an H type 3 fucosylated trisaccharide motif, was recently revealed to also bind to pancreatic ductal adenocarcinoma (PDAC) cells. A lectin‐drug conjugate was generated by fusing rBC2LCN with a cytocidal toxin, and it showed a strong...
Autores principales: | Furuta, Tomoaki, Oda, Tatsuya, Kiyoi, Kayo, Yusuke, Ozawa, Kimura, Sota, Kurimori, Ko, Miyazaki, Yoshihiro, Yu, Yang, Furuya, Kinji, Akashi, Yoshimasa, Shimomura, Osamu, Tateno, Hiroaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409409/ https://www.ncbi.nlm.nih.gov/pubmed/34115906 http://dx.doi.org/10.1111/cas.15023 |
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