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Combining MGMT promoter pyrosequencing and protein expression to optimize prognosis stratification in glioblastoma

Pyrosequencing (PSQ) represents the golden standard for MGMT promoter status determination. Binary interpretation of results based on the threshold from the average of several CpGs tested would neglect the existence of the “gray zone”. How to define the gray zone and reclassify patients in this subg...

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Detalles Bibliográficos
Autores principales: Li, Mingxiao, Dong, Gehong, Zhang, Weiwei, Ren, Xiaohui, Jiang, Haihui, Yang, Chuanwei, Zhao, Xuzhe, Zhu, Qinghui, Li, Ming, Chen, Hongyan, Yu, Kefu, Cui, Yong, Song, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409410/
https://www.ncbi.nlm.nih.gov/pubmed/34115910
http://dx.doi.org/10.1111/cas.15024