Cargando…

The transcription factor RUNX2 fuels YAP1 signaling and gastric cancer tumorigenesis

Despite considerable efforts in the detection and treatment of gastric cancer (GC), the underlying mechanism of the progression of GC remains unknown. Our previous work has demonstrated the remarkable role of Runt‐related transcription factor 2 (RUNX2), in fueling the invasion and metastasis of GC....

Descripción completa

Detalles Bibliográficos
Autores principales:	Guo, Zhengjun, Zhou, Kai, Wang, Qiang, Huang, Yusheng, Ji, Jia, Peng, Yuan, Zhang, Xiaoyue, Zheng, Taihao, Zhang, Zhen, Chong, Daochen, Yang, Zhenzhou
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409423/ https://www.ncbi.nlm.nih.gov/pubmed/34160112 http://dx.doi.org/10.1111/cas.15045

Ejemplares similares

The potential prognostic values of the ADAMTS-like protein family: an integrative pan-cancer analysis
por: Zhang, Xiaoyue, et al.
Publicado: (2021)

Pregnancy Zone Protein Serves as a Prognostic Marker and Favors Immune Infiltration in Lung Adenocarcinoma
por: Chen, Kehong, et al.
Publicado: (2023)

Mechanotransduction and Cytoskeleton Remodeling Shaping YAP1 in Gastric Tumorigenesis
por: Zhang, Jinglin, et al.
Publicado: (2019)

Regulation of the Hippo/YAP axis by CXCR7 in the tumorigenesis of gastric cancer
por: Wang, Tianshi, et al.
Publicado: (2023)

The Multiple Interactions of RUNX with the Hippo–YAP Pathway
por: Chuang, Linda Shyue Huey, et al.
Publicado: (2021)

MCM6 is a critical transcriptional target of YAP to promote gastric tumorigenesis and serves as a therapeutic target
por: Wang, Yifei, et al.
Publicado: (2022)

Phosphorylation of 14-3-3ζ links YAP transcriptional activation to hypoxic glycolysis for tumorigenesis
por: Jia, Yu, et al.
Publicado: (2019)

YAP and β-catenin cooperate to drive H. pylori-induced gastric tumorigenesis
por: Li, Nianshuang, et al.
Publicado: (2023)

NUSAP1 Promotes Gastric Cancer Tumorigenesis and Progression by Stabilizing the YAP1 Protein
por: Guo, Hui, et al.
Publicado: (2021)

YAP promotes tumorigenesis and cisplatin resistance in neuroblastoma
por: Yang, Chao, et al.
Publicado: (2017)

Corrigendum: NUSAP1 Promotes Gastric Cancer Tumorigenesis and Progression by Stabilizing the YAP1 Protein
por: Guo, Hui, et al.
Publicado: (2021)

PKCι and YAP1 are crucial in promoting pancreatic tumorigenesis
por: Wang, Peipei, et al.
Publicado: (2018)

Cyclopeptide RA-V Inhibits Organ Enlargement and Tumorigenesis Induced by YAP Activation
por: Ji, Xinyan, et al.
Publicado: (2018)

RUNX1 and RUNX3 protect against YAP-mediated EMT, stem-ness and shorter survival outcomes in breast cancer
por: Kulkarni, Madhura, et al.
Publicado: (2018)

MST4 kinase suppresses gastric tumorigenesis by limiting YAP activation via a non-canonical pathway
por: An, Liwei, et al.
Publicado: (2020)

Long Non-Coding RNA-PAICC Promotes the Tumorigenesis of Human Intrahepatic Cholangiocarcinoma by Increasing YAP1 Transcription
por: Xia, Long, et al.
Publicado: (2021)

Correction: YAP promotes tumorigenesis and cisplatin resistance in neuroblastoma
por: Yang, Chao, et al.
Publicado: (2022)

miR-301a promotes lung tumorigenesis by suppressing Runx3
por: Li, Xun, et al.
Publicado: (2019)

YAP1 subgroup supratentorial ependymoma requires TEAD and nuclear factor I-mediated transcriptional programmes for tumorigenesis
por: Pajtler, Kristian W., et al.
Publicado: (2019)

Crosstalk Among YAP, LncRNA, and Tumor-Associated Macrophages in Tumorigenesis Development
por: Xu, Jing, et al.
Publicado: (2022)

RUNX3 methylation drives hypoxia-induced cell proliferation and antiapoptosis in early tumorigenesis
por: Lee, Sun Hee, et al.
Publicado: (2020)

Common and Unique Transcription Signatures of YAP and TAZ in Gastric Cancer Cells
por: Lee, Yaelim, et al.
Publicado: (2020)

AP2a enhanced the osteogenic differentiation of mesenchymal stem cells by inhibiting the formation of YAP/RUNX2 complex and BARX1 transcription
por: Lin, Xiao, et al.
Publicado: (2018)

RUNX2 promotes gastric cancer progression through the transcriptional activation of MGAT5 and MMP13
por: Wang, Ying, et al.
Publicado: (2023)

A feed forward loop enforces YAP/TAZ signaling during tumorigenesis
por: Gill, Mandeep K., et al.
Publicado: (2018)

Transcription factors RUNX1 and RUNX3 in the induction and suppressive function of Foxp3(+) inducible regulatory T cells
por: Klunker, Sven, et al.
Publicado: (2009)

Fbxw7 Deletion Accelerates Kras(G12D)-Driven Pancreatic Tumorigenesis via Yap Accumulation()()()
por: Zhang, Qiang, et al.
Publicado: (2016)

C-MYC and BCL-2 mediate YAP-regulated tumorigenesis in OSCC
por: Chen, Xiyan, et al.
Publicado: (2017)

Stem Cell Biomarkers and Tumorigenesis in Gastric Cancer
por: Wuputra, Kenly, et al.
Publicado: (2022)

Aberrant transcriptional and post-transcriptional regulation of SPAG5, a YAP-TAZ-TEAD downstream effector, fuels breast cancer cell proliferation
por: Canu, Valeria, et al.
Publicado: (2020)

Capicua suppresses YAP1 to limit tumorigenesis and maintain drug sensitivity in human cancer
por: Kim, Ji Won, et al.
Publicado: (2022)

Runx transcription factors in neuronal development
por: Inoue, Ken-ichi, et al.
Publicado: (2008)

Feedforward loop between IMP1 and YAP/TAZ promotes tumorigenesis and malignant progression in glioblastoma
por: Yang, Jia, et al.
Publicado: (2023)

Transcription Factors Runx1 and Runx3 Suppress Keratin Expression in Undifferentiated Keratinocytes
por: Ogawa, Eisaku, et al.
Publicado: (2022)

The Influence of Heavy Metals on Gastric Tumorigenesis
por: Wang, Liang, et al.
Publicado: (2022)

YTHDC1-mediated augmentation of miR-30d in repressing pancreatic tumorigenesis via attenuation of RUNX1-induced transcriptional activation of Warburg effect
por: Hou, Yichao, et al.
Publicado: (2021)

Transcription factor RUNX2 up-regulates chemokine receptor CXCR4 to promote invasive and metastatic potentials of human gastric cancer
por: Guo, Zheng-Jun, et al.
Publicado: (2016)

The essential role of YAP O-GlcNAcylation in high-glucose-stimulated liver tumorigenesis
por: Zhang, Xiao, et al.
Publicado: (2017)

A miR-130a-YAP positive feedback loop promotes organ size and tumorigenesis
por: Shen, Shuying, et al.
Publicado: (2015)

PKCι regulates nuclear YAP1 localization and ovarian cancer tumorigenesis
por: Wang, Yin, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_vov24882psp19rul0jf4gamn3c