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MYB mediates downregulation of the colorectal cancer metastasis suppressor heterogeneous nuclear ribonucleoprotein L‐like during epithelial‐mesenchymal transition

Heterogeneous nuclear ribonucleoprotein L‐like (HNRNPLL), a suppressor of colorectal cancer (CRC) metastasis, is transcriptionally downregulated when CRC cells undergo epithelial‐mesenchymal transition (EMT). Here we show that decrease of MYB mediates the downregulation of HNRNPLL during EMT. The pr...

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Detalles Bibliográficos
Autores principales: Sakuma, Keiichiro, Sasaki, Eiichi, Hosoda, Waki, Komori, Koji, Shimizu, Yasuhiro, Yatabe, Yasushi, Aoki, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409424/
https://www.ncbi.nlm.nih.gov/pubmed/34286904
http://dx.doi.org/10.1111/cas.15069