Cargando…

Prediction model of free flaps in microkeratome-assisted LASIK

PURPOSE: To identify mechanical factors, as well as patients’ biometric and surgeons’ experience factors that correlate with the FF incidence in microkeratome (MK)-assisted LASIK and to construct a predictive model based on these parameters. METHODS: 55,700 consecutive LASIK treatments of 28,506 pat...

Descripción completa

Detalles Bibliográficos
Autores principales: Katz, Toam, Druckiv, Vasyl, Siebelmann, Sebastian, Frings, Andreas, Skevas, Christos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409612/
https://www.ncbi.nlm.nih.gov/pubmed/34469435
http://dx.doi.org/10.1371/journal.pone.0255525
_version_ 1783747015328399360
author Katz, Toam
Druckiv, Vasyl
Siebelmann, Sebastian
Frings, Andreas
Skevas, Christos
author_facet Katz, Toam
Druckiv, Vasyl
Siebelmann, Sebastian
Frings, Andreas
Skevas, Christos
author_sort Katz, Toam
collection PubMed
description PURPOSE: To identify mechanical factors, as well as patients’ biometric and surgeons’ experience factors that correlate with the FF incidence in microkeratome (MK)-assisted LASIK and to construct a predictive model based on these parameters. METHODS: 55,700 consecutive LASIK treatments of 28,506 patients between January 2017 and April 2020 done by 50 surgeons in 10 centers, all with Sub Bowman Keratome (SBK) and 90μ head (OUP) were analyzed retrospectively for the incidence of FF and their correlation to mean keratometry, central corneal thickness, MK ring height and stop, as well as surgeons’ experience. A prediction model was built and tested for sensitivity and specificity. RESULTS: The incidence of FF using the SBK MK was 0.276%. Risk factors were low central corneal thickness, very flat (-1) or very thick (+2) ring height, and higher stop values (p<0.001). Mean keratometry and low surgeon experience were not correlated to FF incidence. A prediction model with a cut-off FF risk of 0.274%, a 76% specificity, and a 73% sensitivity was applied. CONCLUSIONS: Free flaps are rarely seen in modern MK LASIK. However, the incidence of this complication using the SBK MK increases using higher stop values, very thick and very thin MK rings, and in eyes with thin corneas.
format Online
Article
Text
id pubmed-8409612
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-84096122021-09-02 Prediction model of free flaps in microkeratome-assisted LASIK Katz, Toam Druckiv, Vasyl Siebelmann, Sebastian Frings, Andreas Skevas, Christos PLoS One Research Article PURPOSE: To identify mechanical factors, as well as patients’ biometric and surgeons’ experience factors that correlate with the FF incidence in microkeratome (MK)-assisted LASIK and to construct a predictive model based on these parameters. METHODS: 55,700 consecutive LASIK treatments of 28,506 patients between January 2017 and April 2020 done by 50 surgeons in 10 centers, all with Sub Bowman Keratome (SBK) and 90μ head (OUP) were analyzed retrospectively for the incidence of FF and their correlation to mean keratometry, central corneal thickness, MK ring height and stop, as well as surgeons’ experience. A prediction model was built and tested for sensitivity and specificity. RESULTS: The incidence of FF using the SBK MK was 0.276%. Risk factors were low central corneal thickness, very flat (-1) or very thick (+2) ring height, and higher stop values (p<0.001). Mean keratometry and low surgeon experience were not correlated to FF incidence. A prediction model with a cut-off FF risk of 0.274%, a 76% specificity, and a 73% sensitivity was applied. CONCLUSIONS: Free flaps are rarely seen in modern MK LASIK. However, the incidence of this complication using the SBK MK increases using higher stop values, very thick and very thin MK rings, and in eyes with thin corneas. Public Library of Science 2021-09-01 /pmc/articles/PMC8409612/ /pubmed/34469435 http://dx.doi.org/10.1371/journal.pone.0255525 Text en © 2021 Katz et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Katz, Toam
Druckiv, Vasyl
Siebelmann, Sebastian
Frings, Andreas
Skevas, Christos
Prediction model of free flaps in microkeratome-assisted LASIK
title Prediction model of free flaps in microkeratome-assisted LASIK
title_full Prediction model of free flaps in microkeratome-assisted LASIK
title_fullStr Prediction model of free flaps in microkeratome-assisted LASIK
title_full_unstemmed Prediction model of free flaps in microkeratome-assisted LASIK
title_short Prediction model of free flaps in microkeratome-assisted LASIK
title_sort prediction model of free flaps in microkeratome-assisted lasik
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409612/
https://www.ncbi.nlm.nih.gov/pubmed/34469435
http://dx.doi.org/10.1371/journal.pone.0255525
work_keys_str_mv AT katztoam predictionmodeloffreeflapsinmicrokeratomeassistedlasik
AT druckivvasyl predictionmodeloffreeflapsinmicrokeratomeassistedlasik
AT siebelmannsebastian predictionmodeloffreeflapsinmicrokeratomeassistedlasik
AT fringsandreas predictionmodeloffreeflapsinmicrokeratomeassistedlasik
AT skevaschristos predictionmodeloffreeflapsinmicrokeratomeassistedlasik