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Prediction model of free flaps in microkeratome-assisted LASIK
PURPOSE: To identify mechanical factors, as well as patients’ biometric and surgeons’ experience factors that correlate with the FF incidence in microkeratome (MK)-assisted LASIK and to construct a predictive model based on these parameters. METHODS: 55,700 consecutive LASIK treatments of 28,506 pat...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409612/ https://www.ncbi.nlm.nih.gov/pubmed/34469435 http://dx.doi.org/10.1371/journal.pone.0255525 |
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author | Katz, Toam Druckiv, Vasyl Siebelmann, Sebastian Frings, Andreas Skevas, Christos |
author_facet | Katz, Toam Druckiv, Vasyl Siebelmann, Sebastian Frings, Andreas Skevas, Christos |
author_sort | Katz, Toam |
collection | PubMed |
description | PURPOSE: To identify mechanical factors, as well as patients’ biometric and surgeons’ experience factors that correlate with the FF incidence in microkeratome (MK)-assisted LASIK and to construct a predictive model based on these parameters. METHODS: 55,700 consecutive LASIK treatments of 28,506 patients between January 2017 and April 2020 done by 50 surgeons in 10 centers, all with Sub Bowman Keratome (SBK) and 90μ head (OUP) were analyzed retrospectively for the incidence of FF and their correlation to mean keratometry, central corneal thickness, MK ring height and stop, as well as surgeons’ experience. A prediction model was built and tested for sensitivity and specificity. RESULTS: The incidence of FF using the SBK MK was 0.276%. Risk factors were low central corneal thickness, very flat (-1) or very thick (+2) ring height, and higher stop values (p<0.001). Mean keratometry and low surgeon experience were not correlated to FF incidence. A prediction model with a cut-off FF risk of 0.274%, a 76% specificity, and a 73% sensitivity was applied. CONCLUSIONS: Free flaps are rarely seen in modern MK LASIK. However, the incidence of this complication using the SBK MK increases using higher stop values, very thick and very thin MK rings, and in eyes with thin corneas. |
format | Online Article Text |
id | pubmed-8409612 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-84096122021-09-02 Prediction model of free flaps in microkeratome-assisted LASIK Katz, Toam Druckiv, Vasyl Siebelmann, Sebastian Frings, Andreas Skevas, Christos PLoS One Research Article PURPOSE: To identify mechanical factors, as well as patients’ biometric and surgeons’ experience factors that correlate with the FF incidence in microkeratome (MK)-assisted LASIK and to construct a predictive model based on these parameters. METHODS: 55,700 consecutive LASIK treatments of 28,506 patients between January 2017 and April 2020 done by 50 surgeons in 10 centers, all with Sub Bowman Keratome (SBK) and 90μ head (OUP) were analyzed retrospectively for the incidence of FF and their correlation to mean keratometry, central corneal thickness, MK ring height and stop, as well as surgeons’ experience. A prediction model was built and tested for sensitivity and specificity. RESULTS: The incidence of FF using the SBK MK was 0.276%. Risk factors were low central corneal thickness, very flat (-1) or very thick (+2) ring height, and higher stop values (p<0.001). Mean keratometry and low surgeon experience were not correlated to FF incidence. A prediction model with a cut-off FF risk of 0.274%, a 76% specificity, and a 73% sensitivity was applied. CONCLUSIONS: Free flaps are rarely seen in modern MK LASIK. However, the incidence of this complication using the SBK MK increases using higher stop values, very thick and very thin MK rings, and in eyes with thin corneas. Public Library of Science 2021-09-01 /pmc/articles/PMC8409612/ /pubmed/34469435 http://dx.doi.org/10.1371/journal.pone.0255525 Text en © 2021 Katz et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Katz, Toam Druckiv, Vasyl Siebelmann, Sebastian Frings, Andreas Skevas, Christos Prediction model of free flaps in microkeratome-assisted LASIK |
title | Prediction model of free flaps in microkeratome-assisted LASIK |
title_full | Prediction model of free flaps in microkeratome-assisted LASIK |
title_fullStr | Prediction model of free flaps in microkeratome-assisted LASIK |
title_full_unstemmed | Prediction model of free flaps in microkeratome-assisted LASIK |
title_short | Prediction model of free flaps in microkeratome-assisted LASIK |
title_sort | prediction model of free flaps in microkeratome-assisted lasik |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409612/ https://www.ncbi.nlm.nih.gov/pubmed/34469435 http://dx.doi.org/10.1371/journal.pone.0255525 |
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