Population Genomics of emm4 Group A Streptococcus Reveals Progressive Replacement with a Hypervirulent Clone in North America

Clonal replacement is a major driver for changes in bacterial disease epidemiology. Recently, it has been proposed that episodic emergence of novel, hypervirulent clones of group A Streptococcus (GAS) results from acquisition of a 36-kb DNA region leading to increased expression of the cytotoxins Ng...

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Detalles Bibliográficos
Autores principales: DebRoy, Sruti, Sanson, Misu, Shah, Brittany, Regmi, Shirjana, Vega, Luis Alberto, Odo, Chioma, Sahasrabhojane, Pranoti, McGeer, Allison, Tyrrell, Gregory J., Fittipaldi, Nahuel, Shelburne, Samuel A., Flores, Anthony R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409732/
https://www.ncbi.nlm.nih.gov/pubmed/34374563
http://dx.doi.org/10.1128/mSystems.00495-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409732/
https://www.ncbi.nlm.nih.gov/pubmed/34374563
http://dx.doi.org/10.1128/mSystems.00495-21

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