Cargando…
Sensitive, homogeneous, and label-free protein-probe assay for antibody aggregation and thermal stability studies
Protein aggregation is a spontaneous process affected by multiple external and internal properties, such as buffer composition and storage temperature. Aggregation of protein-based drugs can endanger patient safety due, for example, to increased immunogenicity. Aggregation can also inactivate protei...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409793/ https://www.ncbi.nlm.nih.gov/pubmed/34455913 http://dx.doi.org/10.1080/19420862.2021.1955810 |