Cargando…

Valuing health states of people with type 2 diabetes: Analyses of the nationwide representative linked databases

AIMS/INTRODUCTION: To estimate preference‐based measures of health‐related quality of life associated with sociodemographic and clinical characteristics in type 2 diabetes patients. MATERIALS AND METHODS: Individuals with EuroQol‐5 dimensions‐3 levels data were identified from Taiwan’s National Heal...

Descripción completa

Detalles Bibliográficos
Autores principales: Kuo, Shihchen, Yang, Chun‐Ting, Chen, Hsuan‐Ying, Ou, Huang‐Tz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409834/
https://www.ncbi.nlm.nih.gov/pubmed/33539655
http://dx.doi.org/10.1111/jdi.13520
_version_ 1783747054380515328
author Kuo, Shihchen
Yang, Chun‐Ting
Chen, Hsuan‐Ying
Ou, Huang‐Tz
author_facet Kuo, Shihchen
Yang, Chun‐Ting
Chen, Hsuan‐Ying
Ou, Huang‐Tz
author_sort Kuo, Shihchen
collection PubMed
description AIMS/INTRODUCTION: To estimate preference‐based measures of health‐related quality of life associated with sociodemographic and clinical characteristics in type 2 diabetes patients. MATERIALS AND METHODS: Individuals with EuroQol‐5 dimensions‐3 levels data were identified from Taiwan’s National Health Interview Survey in 2009 and 2013. Status of diabetes, comorbidities, complications and treatments were ascertained through data linkage to Taiwan’s National Health Insurance Research Database. Multivariable ordinary least squares, Tobit and median regression analyses were used to estimate the coefficients that represented independent impacts of patients’ characteristics on health‐related quality of life. RESULTS: The mean health utility score for 2,104 participants was 0.838. Being female, aging, divorced/widowed, never worked or underweight, or having a lower monthly household income, injectable glucose‐lowering therapy, comorbid connective tissue disease or depression were associated with lower health utilities. Having an amputation led to the largest reduction by 0.288 in health utilities, followed by debilitating stroke (0.266), heart failure (0.237), other coronary heart disease (0.185), kidney dialysis/transplant (0.148), coronary revascularizations (0.093), transient ischemic attack/stroke (0.078), diabetic neuropathy (0.062), polyneuropathy (0.055) and other neuropathy (0.043). CONCLUSIONS: Major vascular complications, connective tissue disease and depression are associated with considerably worse health‐related quality of life. These health utility estimates can facilitate health economic evaluations to determine cost‐effective strategies for diabetes management.
format Online
Article
Text
id pubmed-8409834
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-84098342021-09-03 Valuing health states of people with type 2 diabetes: Analyses of the nationwide representative linked databases Kuo, Shihchen Yang, Chun‐Ting Chen, Hsuan‐Ying Ou, Huang‐Tz J Diabetes Investig Articles AIMS/INTRODUCTION: To estimate preference‐based measures of health‐related quality of life associated with sociodemographic and clinical characteristics in type 2 diabetes patients. MATERIALS AND METHODS: Individuals with EuroQol‐5 dimensions‐3 levels data were identified from Taiwan’s National Health Interview Survey in 2009 and 2013. Status of diabetes, comorbidities, complications and treatments were ascertained through data linkage to Taiwan’s National Health Insurance Research Database. Multivariable ordinary least squares, Tobit and median regression analyses were used to estimate the coefficients that represented independent impacts of patients’ characteristics on health‐related quality of life. RESULTS: The mean health utility score for 2,104 participants was 0.838. Being female, aging, divorced/widowed, never worked or underweight, or having a lower monthly household income, injectable glucose‐lowering therapy, comorbid connective tissue disease or depression were associated with lower health utilities. Having an amputation led to the largest reduction by 0.288 in health utilities, followed by debilitating stroke (0.266), heart failure (0.237), other coronary heart disease (0.185), kidney dialysis/transplant (0.148), coronary revascularizations (0.093), transient ischemic attack/stroke (0.078), diabetic neuropathy (0.062), polyneuropathy (0.055) and other neuropathy (0.043). CONCLUSIONS: Major vascular complications, connective tissue disease and depression are associated with considerably worse health‐related quality of life. These health utility estimates can facilitate health economic evaluations to determine cost‐effective strategies for diabetes management. John Wiley and Sons Inc. 2021-03-02 2021-09 /pmc/articles/PMC8409834/ /pubmed/33539655 http://dx.doi.org/10.1111/jdi.13520 Text en © 2021 The Authors. Journal of Diabetes Investigation published by Asian Association for the Study of Diabetes (AASD) and John Wiley & Sons Australia, Ltd https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Articles
Kuo, Shihchen
Yang, Chun‐Ting
Chen, Hsuan‐Ying
Ou, Huang‐Tz
Valuing health states of people with type 2 diabetes: Analyses of the nationwide representative linked databases
title Valuing health states of people with type 2 diabetes: Analyses of the nationwide representative linked databases
title_full Valuing health states of people with type 2 diabetes: Analyses of the nationwide representative linked databases
title_fullStr Valuing health states of people with type 2 diabetes: Analyses of the nationwide representative linked databases
title_full_unstemmed Valuing health states of people with type 2 diabetes: Analyses of the nationwide representative linked databases
title_short Valuing health states of people with type 2 diabetes: Analyses of the nationwide representative linked databases
title_sort valuing health states of people with type 2 diabetes: analyses of the nationwide representative linked databases
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409834/
https://www.ncbi.nlm.nih.gov/pubmed/33539655
http://dx.doi.org/10.1111/jdi.13520
work_keys_str_mv AT kuoshihchen valuinghealthstatesofpeoplewithtype2diabetesanalysesofthenationwiderepresentativelinkeddatabases
AT yangchunting valuinghealthstatesofpeoplewithtype2diabetesanalysesofthenationwiderepresentativelinkeddatabases
AT chenhsuanying valuinghealthstatesofpeoplewithtype2diabetesanalysesofthenationwiderepresentativelinkeddatabases
AT ouhuangtz valuinghealthstatesofpeoplewithtype2diabetesanalysesofthenationwiderepresentativelinkeddatabases