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Fighting the uphill battle to cure type 1 diabetes

Three complementary approaches for type 1 diabetes. Immunotherapy targets the pathogenic immune cells or inflammatory cytokines to revert type 1 diabetes. An artificial pancreas delivers insulin automatically using continuous glucose monitoring, a controlling algorithm, and an insulin pump. Beta cel...

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Detalles Bibliográficos
Autores principales: Lee, Eun Young, Yoon, Kun‐Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409888/
https://www.ncbi.nlm.nih.gov/pubmed/34110690
http://dx.doi.org/10.1111/jdi.13613
Descripción
Sumario:Three complementary approaches for type 1 diabetes. Immunotherapy targets the pathogenic immune cells or inflammatory cytokines to revert type 1 diabetes. An artificial pancreas delivers insulin automatically using continuous glucose monitoring, a controlling algorithm, and an insulin pump. Beta cell replacement therapy varies depending on the cell sources: allogeneic, or xenogeneic islet; beta‐like cells derived from ESCs or iPSCs.[Image: see text]