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Augmentation of CD47/SIRPα signaling protects cones in genetic models of retinal degeneration
Inherited retinal diseases, such as retinitis pigmentosa (RP), can be caused by thousands of different mutations, a small number of which have been successfully treated with gene replacement. However, this approach has yet to scale and may not be feasible in many cases, highlighting the need for int...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Clinical Investigation
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409989/ https://www.ncbi.nlm.nih.gov/pubmed/34197341 http://dx.doi.org/10.1172/jci.insight.150796 |