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Regulation of PPARα by APP in Alzheimer disease affects the pharmacological modulation of synaptic activity

Among genetic susceptibility loci associated with late-onset Alzheimer disease (LOAD), genetic polymorphisms identified in genes encoding lipid carriers led to the hypothesis that a disruption of lipid metabolism could promote disease progression. We previously reported that amyloid precursor protei...

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Detalles Bibliográficos
Autores principales:	Sáez-Orellana, Francisco, Leroy, Thomas, Ribeiro, Floriane, Kreis, Anna, Leroy, Karelle, Lalloyer, Fanny, Baugé, Eric, Staels, Bart, Duyckaerts, Charles, Brion, Jean-Pierre, Gailly, Philippe, Octave, Jean-Noël, Pierrot, Nathalie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410016/ https://www.ncbi.nlm.nih.gov/pubmed/34228639 http://dx.doi.org/10.1172/jci.insight.150099

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