In vivo grafting of large engineered heart tissue patches for cardiac repair

Engineered heart tissue (EHT) strategies, by combining cells within a hydrogel matrix, may be a novel therapy for heart failure. EHTs restore cardiac function in rodent injury models, but more data are needed in clinically relevant settings. Accordingly, an upscaled EHT patch (2.5 cm × 1.5 cm × 1.5...

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Detalles Bibliográficos
Autores principales: Jabbour, Richard J., Owen, Thomas J., Pandey, Pragati, Reinsch, Marina, Wang, Brian, King, Oisín, Couch, Liam Steven, Pantou, Dafni, Pitcher, David S., Chowdhury, Rasheda A., Pitoulis, Fotios G., Handa, Balvinder S., Kit-Anan, Worrapong, Perbellini, Filippo, Myles, Rachel C., Stuckey, Daniel J., Dunne, Michael, Shanmuganathan, Mayooran, Peters, Nicholas S., Ng, Fu Siong, Weinberger, Florian, Terracciano, Cesare M., Smith, Godfrey L., Eschenhagen, Thomas, Harding, Sian E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410032/
https://www.ncbi.nlm.nih.gov/pubmed/34369384
http://dx.doi.org/10.1172/jci.insight.144068

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