A variant of ASIC2 mediates sodium retention in nephrotic syndrome

Idiopathic nephrotic syndrome (INS) is characterized by proteinuria and renal sodium retention leading to edema. This sodium retention is usually attributed to epithelial sodium channel (ENaC) activation after plasma aldosterone increase. However, most nephrotic patients show normal aldosterone leve...

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Detalles Bibliográficos
Autores principales: Fila, Marc, Sassi, Ali, Brideau, Gaëlle, Cheval, Lydie, Morla, Luciana, Houillier, Pascal, Walter, Christine, Gennaoui, Michel, Collignon, Laure, Keck, Mathilde, Planelles, Gabrielle, Bakouh, Naziha, Peuchmaur, Michel, Deschênes, Georges, Anegon, Ignacio, Remy, Séverine, Vogt, Bruno, Crambert, Gilles, Doucet, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410034/
https://www.ncbi.nlm.nih.gov/pubmed/34166227
http://dx.doi.org/10.1172/jci.insight.148588

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