Deletion of AMPK minimizes graft-versus-host disease through an early impact on effector donor T cells

Allogeneic hematopoietic stem cell transplantation is a viable treatment for multiple hematologic diseases, but its application is often limited by graft-versus-host disease (GVHD), where donor T cells attack host tissues in the skin, liver, and gastrointestinal tract. Here, we examined the role of...

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Detalles Bibliográficos
Autores principales: Monlish, Darlene A., Beezhold, Kevin J., Chiaranunt, Pailin, Paz, Katelyn, Moore, Nathan J., Dobbs, Andrea K., Brown, Rebecca A., Ozolek, John A., Blazar, Bruce R., Byersdorfer, Craig A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410053/
https://www.ncbi.nlm.nih.gov/pubmed/34291733
http://dx.doi.org/10.1172/jci.insight.143811

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