TNFRSF13B polymorphisms counter microbial adaptation to enteric IgA

TNFRSF13B encodes the transmembrane activator and CAML interactor (TACI) receptor, which drives plasma cell differentiation. Although TNFRSF13B supports host defense, dominant-negative TNFRSF13B alleles are common in humans and other species and only rarely associate with disease. We reasoned that t...

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Detalles Bibliográficos
Autores principales: Platt, Jeffrey L., de Mattos Barbosa, Mayara Garcia, Huynh, Daniel, Lefferts, Adam R., Katta, Juhi, Kharas, Cyra, Freddolino, Peter, Bassis, Christine M., Wobus, Christiane, Geha, Raif, Bram, Richard, Nunez, Gabriel, Kamada, Nobuhiko, Cascalho, Marilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410086/
https://www.ncbi.nlm.nih.gov/pubmed/34111031
http://dx.doi.org/10.1172/jci.insight.148208

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