A KCNK16 mutation causing TALK-1 gain of function is associated with maturity-onset diabetes of the young

Maturity-onset diabetes of the young (MODY) is a heterogeneous group of monogenic disorders of impaired pancreatic β cell function. The mechanisms underlying MODY include β cell KATP channel dysfunction (e.g., KCNJ11 [MODY13] or ABCC8 [MODY12] mutations); however, no other β cell channelopathies hav...

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Detalles Bibliográficos
Autores principales: Graff, Sarah M., Johnson, Stephanie R., Leo, Paul J., Dadi, Prasanna K., Dickerson, Matthew T., Nakhe, Arya Y., McInerney-Leo, Aideen M., Marshall, Mhairi, Zaborska, Karolina E., Schaub, Charles M., Brown, Matthew A., Jacobson, David A., Duncan, Emma L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410089/
https://www.ncbi.nlm.nih.gov/pubmed/34032641
http://dx.doi.org/10.1172/jci.insight.138057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410089/
https://www.ncbi.nlm.nih.gov/pubmed/34032641
http://dx.doi.org/10.1172/jci.insight.138057

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